2. Bone and Joint Pain
This is one of the most common symptoms of people who have developed leukemia and is characterized by pain that feels like it originates deep in the bones. This type of pain results from an excess of abnormal white blood cells that accumulate in the bone marrow and causing it to expand. This pain is most common in the long bones such as the legs and arms. There are many other potential causes of bone and joint pain so it would be premature to assume a few aches and pains are the result of leukemia.