3. Headaches
This symptom may not be mentioned as frequently as some of the others but it is something that should not be ignored. The headaches associated with leukemia tend to be long-lasting and can be quite severe. In some cases, a condition called pallor may accompany the headaches and will make the skin color appear significantly more pale or white than normal. Seizures may also be more likely during these episodes as blood supply to the spinal cord and brain can be reduced.